One of the most challenging tasks in clinical trials is finding the maximum tolerated dose (MTD) to be tested in the next phase. An assurance for the safety of the patients and recommendation of a suitable dose for phase II are the main objectives of a phase I trial. The MTD can be identified through various approaches. https://safeersappliancers.shop/product-category/hisense-rs694n4tf1-american-style-fridge-freezer-black-steel/